解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::In a previous paper we demonstrated that the linear portion of the pressure-velocity loop (PU-loop) corresponding to early systole could be used to calculate the local wave speed. In this paper we extend this work to show that determination of the time at which the PU-loop first deviates from linearity provides a conv...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-007-0241-7
更新日期:2007-12-01 00:00:00
abstract::In this study, the shape and the configuration of smooth muscle cells (SMCs) within the arterial wall are altered to investigate their influence on molecular transport across the media layer of the thoracic aorta wall. In a 2D geometry of the media layer containing SMCs, the finite-element method has been employed to ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-007-0219-5
更新日期:2007-11-01 00:00:00
abstract::Very few computer models of the spine integrate vertebral growth plates to investigate their mechanical behavior and potential impacts on bone growth. An approach was developed to generate a finite element (FE) model of the lumbar spine and their connective tissues including the growth plate, which allowed a personali...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-007-0220-z
更新日期:2007-10-01 00:00:00
abstract::Monitoring upper-limb activity in a free-living environment is important for the evaluation of rehabilitation. This study is a validation of the Strathclyde Upper-Limb Activity Monitor (SULAM) which records the vertical movement and position of each wrist, and assesses bimanual movement. Agreement between the SULAM an...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-007-0233-7
更新日期:2007-10-01 00:00:00
abstract::A simple inertial measurement unit (IMU) incorporating rate gyroscopes and accelerometers has been tested to investigate the trunk kinematics during the sit-to-stand. It was affixed at trunk L5 level and used for sit-to-stand position and orientation reconstruction. The method was validated with standard optoelectroni...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-007-0224-8
更新日期:2007-10-01 00:00:00
abstract::The aim of this study was to design a new approach for the acquisition of regional radial strain from the middle portion of the interventricular septum. We designed and wrote a program in Matlab (computer-assisted method) for use on a personal computer so that the septum thickness throughout the cardiac cycle could be...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-007-0222-x
更新日期:2007-09-01 00:00:00
abstract::Partial coherence estimate between two signals removing the contribution of a periodic, deterministic one is proposed for measuring the coherence between two ongoing eletroencephalografic (EEG) activities collected at distinct cortical regions under sensory stimulation. The estimator expression was derived and shown t...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-007-0191-0
更新日期:2007-07-01 00:00:00
abstract::The physiological parameters of blood such as extracellular Na(+), K(+), Cl(-), pH, 2,3-DPG and ATP and the complex electrical impedance were measured using whole blood samples from 31 male donors (21 donors form the training set and ten donors were used for testing), on the 0th, 10th and 21st day of blood bank storag...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-007-0206-x
更新日期:2007-07-01 00:00:00
abstract::Measurements of the dielectric properties of healthy and atherosclerotic human artery tissues were made in the frequency range of 100 Hz-100 kHz and temperatures from 22 to 260 degrees C. The temperature dependencies of the dielectric parameters for healthy tissues reveal distinctively the temperature ranges correspon...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-007-0181-2
更新日期:2007-06-01 00:00:00
abstract::The surface electroenterogram (EEnG) is a non-invasive method of studying myoelectrical bowel activity. However, surface EEnG recordings are contaminated by cardiac activity, respiratory and motion artifacts, and other sources of interference. The aim of this work is to remove the respiration artifact and the very low...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-007-0189-7
更新日期:2007-06-01 00:00:00
abstract::In this paper, a comparative evaluation of state-of-the art feature extraction and classification methods is presented for five subjects in order to increase the performance of a cue-based Brain-Computer interface (BCI) system for imagery tasks (left and right hand movements). To select an informative feature with a r...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-007-0169-y
更新日期:2007-04-01 00:00:00
abstract::Generation of a large number of cells belonging to the cardiac pacemaker system would constitute an important step towards their utilization as a biological cardiac pacemaker system. The aim of the present study was to identify factors, which might induce transformation of a heterogenous population of fetal cardiomyoc...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-007-0164-3
更新日期:2007-02-01 00:00:00
abstract::Spontaneous activity of specific regions (e.g., the Sinoatrial node, SAN) is essential for the normal activation sequence of the heart and also serve as a primary means of modulating cardiac rate by sympathetic tone and circulating catecholamines. The mechanisms of how a small SAN region can electrically drive a much ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章,评审
doi:10.1007/s11517-006-0102-9
更新日期:2007-02-01 00:00:00
abstract::Biological variation in branching patterns is likely to affect perfusion of tissue. To assess the fundamental consequences of branching characteristics, 50 stochastic asymmetrical coronary trees and one non-stochastic symmetrical branching tree were generated. In the stochastic trees, area growth, A, at branching poin...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-006-0139-9
更新日期:2007-01-01 00:00:00
abstract::One of the most common cancer types among women is breast cancer. Regular mammographic examinations increase the possibility for early diagnosis and treatment and significantly improve the chance of survival for patients with breast cancer. Clustered microcalcifications have been considered as important indicators of ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-006-0117-2
更新日期:2006-11-01 00:00:00
abstract::Architectural distortion is a subtle abnormality in mammograms, and a source of overlooking errors by radiologists. Computer-aided diagnosis (CAD) techniques can improve the performance of radiologists in detecting masses and calcifications; however, most CAD systems have not been designed to detect architectural dist...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-006-0088-3
更新日期:2006-10-01 00:00:00
abstract::One challenge in the current research of brain-computer interfaces (BCIs) is how to classify time-varying electroencephalographic (EEG) signals as accurately as possible. In this paper, we address this problem from the aspect of updating feature extractors and propose an adaptive feature extractor, namely adaptive com...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-006-0107-4
更新日期:2006-10-01 00:00:00
abstract::A simple objective screening method for diagnosis of the atrial septal defect (ASD) is needed. Acoustic signals were collected from 61 children with ASD and 60 with a physiological murmur. The second heart sound (S2) and the spectrum of systolic murmur were analysed. A statistical model was designed using stepwise log...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-006-0094-5
更新日期:2006-09-01 00:00:00
abstract::Mammography is a widely used screening tool and is the gold standard for the early detection of breast cancer. The classification of breast masses into the benign and malignant categories is an important problem in the area of computer-aided diagnosis of breast cancer. A small dataset of 57 breast mass images, each wi...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-006-0077-6
更新日期:2006-08-01 00:00:00
abstract::The long QT syndrome (LQTS) is a genetic disorder, typically characterized by a prolonged QT interval in the ECG due to abnormal cardiac repolarization. LQTS may lead to syncopal episodes and sudden cardiac death. Various parameters based on T-wave morphology, as well as the QT interval itself have been shown to be us...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-006-0061-1
更新日期:2006-07-01 00:00:00
abstract::In the routine recording of magnetocardiograms (MCGs), it is necessary to underline the problem of noise cancellation. Source separation has often been suggested to solve this problem. In this paper, blind source separation (BSS), by means of singular value decomposition (SVD) and independent component analysis (ICA),...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-006-0055-z
更新日期:2006-06-01 00:00:00
abstract::A nonlinear prediction method for investigating the dynamic interdependence between short length time series is presented. The method is a generalization to bivariate prediction of the univariate approach based on nearest neighbor local linear approximation. Given the input and output series x and y, the relationship ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-006-0043-3
更新日期:2006-05-01 00:00:00
abstract::The aim of this study was to analyse the trends of the first three power spectral moments of the mechanomyogram (MMG) signal recorded by a microphone (MMG(MIC)) and an accelerometer (MMG(ACC)) during sustained contractions. MMG signals were recorded from the biceps brachii muscle in 14 healthy male subjects during a 3...
journal_title:Medical & biological engineering & computing
pub_type: 临床试验,杂志文章
doi:10.1007/s11517-006-0036-2
更新日期:2006-04-01 00:00:00
abstract::Cardiotocography is the most diffused prenatal diagnostic technique in clinical routine. The simultaneous recording of foetal heart rate (FHR) and uterine contractions (UC) provides useful information about foetal well-being during pregnancy and labour. However, foetal electronic monitoring interpretation still lacks ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-006-0022-8
更新日期:2006-03-01 00:00:00
abstract::Implantable cardioverter defibrillators (ICDs) can store intracardiac electrograms (EGMs) in sinus rhythm (SR), at the onset of spontaneous ventricular tachyarrhythmias (VT) or during their course. This allows the investigation of unknown features of the heart electrical activity associated with different cardiac rhyt...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-005-0014-0
更新日期:2006-03-01 00:00:00
abstract::The successful decoding of kinematic variables from spike trains of motor cortical neurons is essential for cortical neural prosthesis. Spike trains from each single unit must be extracted from extracellular neural signals and, thus, spike detection and sorting procedure is indispensable but the detection and sorting ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-005-0009-x
更新日期:2006-03-01 00:00:00
abstract::High-intensity noises are a health hazard for industrial workers, and hearing protection is necessary to prevent hearing loss. Passive methods, such as ear muffs, are ineffective against low-frequency noise. Moreover, many hearing-impaired workers must wear hearing aids to enable communication at their workplace, and ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02430951
更新日期:2005-11-01 00:00:00
abstract::Electrocardiogram (ECG)-triggered laser Doppler perfusion monitoring (LDPM) was used to assess myocardial perfusion, with minimum myocardial tissue motion influence, during coronary artery bypass grafting (CABG). Thirteen subjects were investigated at six phases: pre- and post-CABG; post aorta cross-clamping; pre and ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02351031
更新日期:2005-09-01 00:00:00
abstract::Preprocessing, binning and dataset subsampling are investigated with regard to simultaneous maximisation of the speed, accuracy and robustness of CT-3D rotational angiography (3DRA) registration. Clinical diagnosis and treatment can both take advantage of this integration, because 3DRA allows the shape of vessel struc...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02351041
更新日期:2005-09-01 00:00:00
abstract::From adult data, it is known that numerous factors, such as age, state of the autonomic nervous system, diurnal rhythms or mean R-R interval mRR, influence heart rate variability (HRV). The aim of this study was the examination of the influence of gestational age, mRR, gender and time of day on fetal HRV. The analysis...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02344729
更新日期:2005-07-01 00:00:00
abstract::This study introduced the Kalman filter procedure for tracking urinary bladder filling from intermittent bladder volume measurements taken by an ultrasonic bladder volume monitor. The Kalman filter was based on a double integrator as a model for the bladder filling process between micturitions and included a procedure...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02345809
更新日期:2005-05-01 00:00:00
abstract::The software system GASepo has been developed as a tool to visualise and analyse doping (searching for performance-enhancing drugs in sports) with recombinant erythropoietin (rEpo). Digital images derived from the separation of Epo isoforms in gels by iso-electric focusing followed by double blotting and chemiluminesc...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02345819
更新日期:2005-05-01 00:00:00
abstract::Heart sounds can be considered as mechanical fingerprints of myocardial function. The third heart sound normally occurs in children but disappears with maturation. The sound can also appear in patients with heart failure. The sound is characterised by its low-amplitude and low-frequency content, which makes it difficu...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02345957
更新日期:2005-03-01 00:00:00
abstract::A comparison of auditory and visual perception of scatterplots showed similar correlation estimation performance in both modalities. The present study replicated this experiment using electrotactile (electrocutaneous) presentation of scatterplots on the fingertips and abdomen, as well as visual presentation. The corre...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02345967
更新日期:2005-03-01 00:00:00
abstract::Vascular access for renal dialysis is a lifeline for about 120 000 individuals in the United States. Stethoscope auscultation of vascular sounds has some utility in the assessment of access patency, yet can be highly skill-dependent. The objective of the study was to identify acoustic parameters that are related to ch...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02345123
更新日期:2005-01-01 00:00:00
abstract::The purpose of this study was to evaluate the effect of increased blood flow on angiogenesis at the large vessels. The arteriovenous (AV) shunt was made on the thigh of male Wistar rats (n = 27) to increase blood flow, wrapped with artificial skin dermis, which consisted of a silicon outer layer, and isolated from sur...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02345133
更新日期:2005-01-01 00:00:00
abstract::Uniaxial stress-strain data were obtained from in vitro experiments on 20 porcine livers for compressions, elongations and cycles of compression and then elongation. There were about 70 cylindrical samples, with diameter 7mm and varying height (4-11 mm). The combined compression and elongation test provide a unified f...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02345212
更新日期:2004-11-01 00:00:00
abstract::Functional magnetic resonance imaging (FMRI) is an imaging technique for determining which regions of the brain are activated in response to a stimulus or event. Early FMRI experiment paradigms were based upon those used in positron emission tomography (PET), i.e. employing a block design consisting of extended period...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02347541
更新日期:2004-09-01 00:00:00
abstract::A generic framework for the automated classification of human movements using an accelerometry monitoring system is introduced. The framework was structured around a binary decision tree in which movements were divided into classes and subclasses at different hierarchical levels. General distinctions between movements...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02347551
更新日期:2004-09-01 00:00:00
abstract::A computational model of the fluid dynamics of intraventricular flow was used to investigate the importance of the effects of flow disturbances existing within the left ventricle (LV) at the onset of diastole on a diastolic flow field. The simulation started with a quiescent flow state; it continued for a number of ca...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02350992
更新日期:2004-07-01 00:00:00